The draw for the first stage was held on 21 December 2022, 12:00 PYST (UTC−3), at the CONMEBOL Convention Centre in Luque, Paraguay.
[2] For the first stage, the 32 teams involved were divided into eight pots according to their national association.
[3] If tied after 90 minutes, extra time would not be played, and a penalty shoot-out would be used to determine the winner (Regulations Article 2.4.2).
Academia Puerto Cabello advanced to the group stage (VEN 1).
Estudiantes de Mérida advanced to the group stage (VEN 2).