Grid positions 39 and 40 are filled by the two "Open" (teams without a charter) cars that set the fastest times in qualifying, but did not lock in a spot in the Duels.
The fastest two Open team qualifiers were Jimmie Johnson and Travis Pastrana which earned them a spot in the race regardless of the outcome of the Duels.
[18] Brad Keselowski was the fastest in the final practice session with a time of 47.071 seconds and a speed of 191.201 mph (307.708 km/h).
10 laps in, the inside line began to show its strength, with Larson, Joey Logano, and Christopher Bell making up the top 3 of the field.
After the pit cycle, Denny Hamlin took the lead, but was passed by Chase Briscoe on lap 42, as two lines have formed again.
After another sequence of pit stops, the pack went three wide on lap 112, with Logano and Ryan Blaney leading the race.
Reddick, Erik Jones and Chase Elliott retired from the race, while Blaney received repairs on his right front.
Between laps 176 and 180, drivers began making their final pit stops, with Harrison Burton taking the lead after the cycle.
With 18 laps to go, the first Big One takes place, with Preece losing control and making a heavy impact on the wall before collecting Harvick, Truex, Johnson, and Chase Briscoe.
The race restarts with 14 laps to go, with Burton leading on the outside pushed by Busch, and Logano on the inside with William Byron.
With four laps to go, the RCR drivers coordinated with Byron on the back straight to pass Keselowski and Buescher, with Busch taking the lead, looking for his first Daytona 500 victory in his 18th attempt.
On the back straight, Stenhouse, with a push from Larson, passed Logano, and the yellow flag was waved seconds later for another Big One, caused by Byron's touch on Dillon who spun up the track collecting Cindric, Burton, Hamlin, Johnson, Gragson, Todd Gilliland, and Zane Smith.
Stenhouse grew his lead to a stable amount coming to the white flag, blocking the inside line, leaving Larson without a draft.
In turn 2, Almirola bumped Travis Pastrana who lost control and spun, creating the third Big One with Keselowski, Almirola, Busch, Wallace, Allmendinger and Hamlin involved, and the yellow flag was quickly waved, ending the race as the white flag had already flown, with Stenhouse in the lead.
1992 and 1998 Daytona 500 winning crew chief Larry McReynolds provided insight from the Fox Sports studio in Charlotte.
The booth crew consists of Alex Hayden, Jeff Striegle, and 1989 Cup Series champion Rusty Wallace.
On pit road, MRN was operated by Steve Post, Kim Coon, Brienne Pedigo and Dillon Welch.