Daniil Medvedev defeated the defending champion Andrey Rublev in the final, 6–2, 6–2 to win the men's singles tennis title at the 2023 Dubai Tennis Championships.

[1] It was Medvedev's third ATP Tour title in as many weeks, following championships in Rotterdam and Doha.

Djokovic retained the top ranking after Alcaraz withdrew from Acapulco sidelined due to injury sustained in Rio the previous week.

[2] Medvedev ended Djokovic's 21-match winning streak in the semifinals which dated back to 2022 ATP Finals.

This tournament marked the retirement of former top-50 player Malek Jaziri.