She beat her Dutch rival Demi Vollering of SD Worx by just nine seconds, with Italian Gaia Realini of Trek–Segafredo in third place.

[9] The race started in Torrevieja on the Costa Blanca[10] with a team time trial, before heading north with stages through Castilla–La Mancha, Community of Madrid and Castile and León.

[15] Three-time Giro Donne winner and 2022 Tour de France Femmes winner Annemiek van Vleuten praised the 2023 route, calling it "a very complete Vuelta",[16] and welcomed that the inclusion of the Lagos de Covadonga climb on the final stage, stating "to end in such a famous location is essential for the race".

[17] Prior to the start of the race, Annemiek van Vleuten, Demi Vollering, Gaia Realini, Mavi García, Kasia Niewiadoma and Juliette Labous were all named as pre-race favourites for the general classification (GC),[19][20] with Charlotte Kool, Emma Norsgaard and Marianne Vos tipped for the points classification.

[20] Potential contender for the general classification Elisa Longo Borghini announced that she would miss the race due to a stomach bug.