Petra Kvitová defeated Elena Rybakina in the final, 7–6(16–14), 6–2 to win the women's singles tennis title at the 2023 Miami Open.

Rybakina was attempting to complete the Sunshine Double, having already won the title at Indian Wells.

[1] Iga Świątek was the reigning champion,[2] but withdrew before the tournament began due to injury.

Click on the seed number of a player to go to their draw section.

† The player was not required to count points for the 2022 tournament due to a long-term injury exception.