The tournament is reserved for teams indirectly affiliated to the Asociación del Fútbol Argentino (AFA), while teams affiliated to AFA have to play the Primera B Metropolitana, which is the other third tier competition.
The losing teams were relegated to the Torneo Regional Federal Amateur.
The teams will be seeded in each round according to their final placement in the first stage of the tournament.
In all rounds except for the final, the higher-seeded team will advance in case of a tie, with extra time and a penalty shoot-out set to be played in case of a draw in the final.
[1] The loser of fourth knockout round will play a Promotion playoff against one team from Primera B Metropolitana.