The 2024–25 EuroCup Women knockout stage details the matches played to decide the champion of the tournament.
Games took place between the 12 December 2024 and 8 April 2025.
28 teams from the regular season advanced to knockout stage alongside four teams from the EuroLeague Women who dropped down to this tournament due to them finishing last in the first round of the EuroLeague Women.
[1] The seeding was based on the results of the previous round.
The four eliminated teams from the EuroLeague Women were pre-seeded into positions 1–4.