The 2024–25 Louisville Cardinals women's basketball team will represent the University of Louisville during the 2024–25 NCAA Division I women's basketball season.

The Cardinals will be led by eighteenth-year head coach Jeff Walz, and will play their home games at the KFC Yum!

This season will be their eleventh year competing in the Atlantic Coast Conference.

They received an at-large invitation to the NCAA Tournament, marking the thirteenth straight time the Cardinals qualified for the tournament.

As the sixth seed in the Albany 2 they were upset by eleventh seed Middle Tennessee in the First Round to end their season.