During the regular season, each team plays each other once (either at home or at away).
The top eight teams from the regular season face each other twice more (once at home and once away), with the top two teams earning promotion to the 2025–26 Maltese Premier League.
Results from the regular season were carried over into this round.
The bottom eight teams from the regular season face each other for the second time (either at home or away), with the bottom four teams being relegated to the 2025–26 Maltese National Amateur League.
Results from the regular season were carried over into this round.