The 2024–25 Youngstown State Penguins women's basketball team represents Youngstown State University during the 2024–25 NCAA Division I women's basketball season.

The Penguins, led by first-year head coach Melissa Jackson, play their home games at the Beeghly Center in Youngstown, Ohio as members of the Horizon League.

[3] On October 2, 2023, it was announced that head coach John Barnes would be taking a leave of absence to focus on "personal family matters," with associate head coach John Nicolais serving as acting head coach in Barnes' absence.

[4] On January 19, 2024, Barnes announced that he would be stepping down after ten years at the helm, with associate head coach John Nicolais serving as interim head coach for the remainder of the season.

[5] On March 14, 2024, the school announced that they would be hiring former Akron head coach and Cleveland State assistant Melissa Jackson as the team's new head coach.