Incumbent Republican mayor Dave Bronson ran for re-election to a second term in office.
Bronson's general election vote total was the lowest for an incumbent Anchorage mayor since 2009.
Candidates eliminated in the general election include nonprofit executive Bill Popp and former Alaska House Majority Leader Chris Tuck.
Popp endorsed LaFrance in the runoff, while Tuck remained neutral.
LaFrance prevailed in the runoff, becoming the first woman elected mayor of Anchorage.