Incumbent Democratic Senator Sherrod Brown lost re-election to a fourth term, being defeated by Republican nominee Bernie Moreno.

[1][2] Along with Bob Casey Jr. in Pennsylvania and Jon Tester in Montana, Brown was one of three incumbent Senators to lose re-election in 2024.

[5][6] Although Brown outperformed Kamala Harris in the concurrent presidential election, receiving around 2.6% more of the vote, it was still not enough to win.

After voting for President Barack Obama in both 2008 and 2012, Ohio has trended increasingly Republican in subsequent years and is now considered a red state.

If he had been reelected he would have been only the second Ohioan to be elected to the United States Senate four times, the other being John Glenn[9][10][11][12] Brown led most polls for most of the year.