Arizona is led by second-year head coach Brent Brennan, following the departure of Jedd Fisch to Washington.

Despite high regular season expectations off of their previous season, including a #21 ranking in the preseason AP poll, the Wildcats regressed under Brennan, finishing 4–8 overall (2–7 in conference play) and failing to qualify for a bowl game for the sixth time in seven seasons.

Thirty-two Arizona players elected to enter the NCAA Transfer Portal during or after the 2024 season.

Δ= TBD left the Arizona program following signing but prior to the 2025 season.

2025 overall class rankings Over the off-season, Arizona added twenty-six players from the transfer portal.