The 2025 UTSA Roadrunners football team will represent the University of Texas at San Antonio in the American Athletic Conference (AAC) during the 2025 NCAA Division I FBS football season.

The Roadrunners will be led by Jeff Traylor in his sixth year as the head coach.

The Roadrunners will play their home games at the Alamodome, located in San Antonio, Texas.

Over the off-season, UTSA has lost twelve players through the NCAA transfer portal.

[3][4] On July 25, 2024, UTSA completed their scheduling of nonconference opponents with a game against Incarnate Word from the Southland Conference.