The awards were arranged by the Academy of Interactive Arts & Sciences (AIAS).

Summit, and was co-hosted by Jessica Chobot of Nerdist News, and Kinda Funny co-founder Greg Miller.

The winners were announced in a ceremony at the Mandalay Bay Resort in Las Vegas on February 24, 2022 (2022-02-24).

Ed Boon, co-creator of the Mortal Kombat franchise, was inducted into the Academy's Hall of Fame.

[5] Winners are listed first, highlighted in boldface, and indicated with a double dagger (‡).