As soon as it was mustered in the Regiment was sent north to help deal with the Sioux uprising in Minnesota.

Iowa was in the Army's newly formed Department of the Northwest commanded Major General John Pope at Fort Snelling.

A total of 1172 men served in the 27th Iowa at one time or another during its existence.

[2] It suffered 1 officer and 23 enlisted men who were killed in action or who died of their wounds and 2 officers and 167 enlisted men who died of disease, for a total of 193 fatalities.

This article about a specific military unit of the American Civil War is a stub.