She is the sistership of MV 2GO Masikap Ships that was once part of the fleet of 2GO Travel that were either scrapped, sunk, or sold for various reasons.

2012–2019 Their first livery is composed of an all-white color dominating the ship with the funnel and the waterline painted with magenta.

The sides of the hull featured the "2GO Travel" branding as well as the then company's signature logo, a large stylized letter "G" painted near the bow and to the funnel.

On June 15, 2013, MV St. Gregory the Great, bound from Iloilo to Bacolod and Cagayan de Oro allegedly took a wrong shortcut and was involved in a grounding incident off Siete Pecados Islands near Iloilo and Guimaras, damaging its hull and flooding its engine room with seawater.

On August 16, 2013, at 9 pm as it approached Cebu City's harbor, MV St. Thomas Aquinas,[46] collided with the cargo ship MV Sulpicio Express Siete of Philippine Span Asia Carrier Corporation and sank in 100 feet deep off Talisay, Cebu.

[47] MV Sulpicio Express Siete with 36 crew members on board did not sink and returned safely to port.

[47] On August 7, 2021, MV St. Anthony de Padua was undergoing quarantine in Bauan, Batangas after 28 of the 82 crew members aboard tested positive for the coronavirus disease 2019.

[48] The Maritime Industry Authority (MARINA) in Calabarzon suspended the vessel's passenger safety certificate, and Transport Secretary Arthur Tugade tasked MARINA, the Philippine Ports Authority (PPA), and the Philippine Coast Guard (PCG) to investigate possible lapses leading to the incident.

[49] On June 8, 2024, MV St Francis Xavier experienced engine trouble while departing Coron and bound to Puerto Princesa.

During its undocking maneuver, the vessel lost all power and was left dead in the water so the crew anchored the ship to prevent it from drifting.

While engineers worked on restoring power, the vessel's stern ran aground in a shallow area near the pier due to low tide.