[5] While participating in a practice landing against Mele Bay, Efate on November 8, the battalion was also preparing to receive 50 new LVT-2 amphibian tractors.

Of 125 vehicles used (50 new LVT-2s and 75 LVT-1s),[5] only 35 remained operational by the end of the first day, continuing to ferry men and supplies across the coral reef and through the shallows to the beach.

[8] Among the dead was the battalion's commanding officer, Major Henry C. Drewes, who was posthumously awarded the Silver Star for his heroic actions under fire before being killed on the first day of the battle.

[12] On July 24, 1944, the 2nd Amphibian Tractor Battalion with 96 LVT-2s and 40 LVT-4s, brought the 24th Marine Regiment ashore during the Battle of Tinian,[13] After the surrender of Japan in August 1945, the battalion returned to the United States and was decommissioned on November 29, 1945, at Marine Corps Base Camp Pendleton, California.

Elements of deployed in support of Multinational Force Beirut Lebanon 1983–1985 as part of the 24th Marine Amphibious Unit (MAU).

Elements of the battalion participated in Operation Urgent Fury in Grenada in 1983 as part of the 22nd Marine Amphibious Unit (MAU).

The AAV platoon was used as rifleman and as a reactionary force in support of Golf Company during the reinforcement of the American Embassy in Monrovia, Liberia during Operation Assured Response.

The battalion was deployed to the Middle East in 2003 and took part in Operation Iraqi Freedom I providing mechanized support for the infantry regiments.

Elements of Company C deployed to the Helmand Province with Battalion Landing Team 1/6 as part of the 24th Marine Expeditionary Unit.

Fourth Platoon was attached to 1st Battalion, 3d Marines and conducted provisional infantry missions from two combat outposts.

After supporting clearing operations with the 3/4/205 Afghan National Army battalion, the platoon provided security at the Marjeh Government Center and for the District Governor.

Elements of 1st Platoon also participated in route security and screening missions during the preparations phase of Operation Moshtarak.

Its 321-day duration fell eight days short of the record set in 1973 by the aircraft carrier USS Midway for the longest U.S. Navy deployment since World War II.

The 22nd MEU was awarded the Meritorious Unit Commendation and the NATO Non-Article 5 Medal for Operation Unified Protector.