However, the only personnel actually assigned to the regiment were a small cadre of Regular Army soldiers charged with the task of preparing for the thousands of young draftees who would soon be flooding the camp.
The War Department issued orders instructing the 82nd Division to send all of its soldiers, minus a 783-man training cadre, to other camps to create new units.
In April 1918, the regiment received orders to move to Camp Upton, New York in preparation for embarkation to France.
The German Army's Spring Offensive, launched on March 21, 1918, was a desperate attempt to win the war then and there, before the strength of the American Expeditionary Force (AEF) on the Western Front, then consisting of only a few divisions, became overwhelming.
Other attacks along the Somme, Lys, and Aisne Rivers had stretched the British and French Armies, both, after nearby four years of war, critically short of manpower, to their absolute limits.
Upon their arrival at the French port of Le Havre, on May 17, 1918 the regiment began sending small detachments into the lines to accustom the men to the brutal realities of trench warfare.
The 326th went "over the top", advancing behind an artillery barrage to capture 3 German machine guns, inflict 73 casualties, and secure the information needed by higher headquarters.
Through ten days of battle, the regiment, sustaining heavy casualties, was able to punch a hole in the German Army's last line of defense.
After occupation duties, the regiment returned to the United States in April 1919, and was demobilized at Camp Mills, New York.
The 326th Infantry Regiment was reconstituted as an Organized Reserve unit on 24 July 1921, assigned to the 82nd Division, and allotted to the IV Corps Area.
The 326th Infantry Regiment was composed, as it was in World War I, of large numbers of draftees and went through its basic training at Camp Claiborne, Louisiana.
The division was to take part in the Allied invasion of Sicily, codenamed Operation Husky, then scheduled for June 10, 1943, although it was eventually postponed by a month.
Training continued until, in October 1944, the division, now brought up to strength, was alerted for service overseas in Western Europe and began preparations for movement.
Together with the rest of the division, the regiment, as it did in World War I, landed at Le Havre, France, in February 1945 and moved forward to a staging area.