The 328th Bombardment Squadron received a Distinguished Unit Citation for its gallantry during the raid on the Ploiești, Romania oil refineries in August 1943.

The squadron also flew tactical bombing raids against Afrika Korps defensive positions in Tunisia, supporting the British Eighth Army forces in their advance to Tunis, in September and October 1943.

From England, it resumed long-range strategic bombardment raids on Occupied Europe and Nazi Germany, attacking enemy military and industrial targets as part of the United States' air offensive.

The squadron was one of the most highly decorated units in the Eighth Air Force, continuing offensive attacks until the German capitulation in May 1945.

[citation needed] In June 1945, the squadron returned to the United States, being remanned and re-equipped with Boeing B-29 Superfortress heavy bombers.

[citation needed] During the Cold War, the squadron was equipped with new weapons systems as they became available, performing strategic bombardment training with the Boeing B-50 Superfortress, an advanced version of the B-29 in 1950.

The B-50 gave the unit the capability to carry heavy loads of conventional weapons faster and farther as well as being designed for atomic bomb missions if necessary.

[citation needed] By 1951, the emergence of the Soviet MiG-15 interceptor in the skies over North Korea signaled the end of the propeller-driven B-50 as a first-line strategic bomber.

[citation needed] The squadron deployed aircraft and personnel to the 1708th Provisional Bombardment Wing at Prince Abdullah Air Base, Jeddah, Saudi Arabia, from August 1990 and to the 4300th Provisional Bombardment Wing at Diego Garcia Air Base, British Indian Ocean Territories from January 1991 for Operation Desert Storm.