On 1 April 1944, the group re-formed as a Boeing B-29 Superfortress-equipped unit as part of the 314th Bombardment Wing and trained for deployment to the Pacific Theater against Japan.

Upon activation 6 July 1942, the 330th Bombardment Group (Heavy) was assigned to Second Air Force as a Consolidated B-24 Liberator Replacement Training Unit (RTU).

The Group began its deployment to North Field, Guam in early 1945, and was assigned to the XXI Bomber Command of the Twentieth Air Force.

The Group's advanced ground echelon left Walker AAF by train on 7 January 1945 for the Fort Lawton Staging Area in Seattle, Washington.

Once back in Kansas in early March, they picked up their new Boeing B-29 Superfortresses and headed to Guam via Mather Field, California, Hawaii and Kwajalein.

The sixty or so aircraft that made up the 330th were divided among three Bombardment Squadrons (BS): On their vertical stabilizers they wore a 12-foot (4 m) square black box unit identification mark with a large capital letter K superimposed.

A major reason was the weather which hindered both assembling in formation at a remote point and then flying to the target, which might be covered in clouds or haze making visual bombing difficult or impossible.

On a typical daylight mission, aircraft flew individually, one minute apart, from Guam to a predesignated "rallying" point about 100 miles (160 km) off the coast of Japan.

The aircraft flew thousands of miles for 12 or more hours, and had to conserve as much fuel as possible in order to make it back to base or to Iwo Jima.

The 330th BG contributed 16 aircraft that deposited 47.5 tons on or near its aiming point (AP) described as the Tokyo Artificial Chemical Fertilizer Plant.

The Group was part of a 457 effort by the XXI Bomber Command in its continuing campaign to knock out the major Japanese industrial cities.

Keyes states that they took off at 02:40 (military time zone G) and assembled in loose formation at Iwo Jima and proceeded through soupy weather to the empire.

Planes proceeded to the Japanese mainland at about 10,000 feet (3,000 m) and, in the case of Keyes, arrived early and circled for 30 minutes before finding their formation.

As part of a large armada of 494 B-29s from the XXI BC that attacked the Amagasaki urban area northwest of Osaka, the 330th BG contributed 26 planes to the raid.

Osaka, as a result of these fire raids, as well as the strangulation on their food and raw materials caused by aerial mining, ceased to function as a viable city by the end of July 1945.

This seemingly insignificant raid was in fact the start of an intensive bombing campaign of cities and the railroad system on this coast since it was directly in the path of the projected invasion of Kyūshū by Gen. Douglas MacArthur on 1 November 1945.

The citation stated: " This source of power was permanently eliminated as a target and 2/3 of its industrial region was leveled in this magnificent demonstration of determination and bombing skill".

The Japanese were aware that this was an important target as well; they sent up night fighters (they had very few) and shot down one B-29 and badly damaged another -neither plane from the 330th BG -but the demise of the B-29 was vividly described by the returning crews.

Several crews saw a B-29 with one engine flaming, fired on by two sets of tracers 10 miles (16 km) beyond the target area; it exploded once in the air and again when it hit the ground at 27/0158G.

In the first instance one aircraft had on board Ray Clark, a newsman from Station WOW, Omaha who broadcast live back to Guam and the States.

The second highlight of the mission was that the City of Ogaki was part of a 20th Air Force Psychological Warfare Effort involving the Japanese people.

The crews due to the pamphlets forewarning the Japanese of the attack and the clear night, which made a raid likely, believed the aggressive defenses.

A minor city, Nishinomiya, population 112,000 between Kobe and Osaka was attacked this night with 6/10 cloud cover over the target during the bomb run.

This time against the Kumagaya urban area with a population of 47,000 located northwest of Tokyo but it was on a main rail line to the West Coast.

Further reports stated that the foils falling across bare electric power and communication lines shorted them out, further complicating Japanese existence.

On the regular BG missions, the RCM observer would spot or barrage jam the detected Japanese signals but, since the aircraft would be in the area for only 10 to 15 minutes, it was not effective during the entire time that the group was over the target.

RCM activities were very effective based on numerous crew reports of searchlights frantically searching the sky with little degree of accuracy when there was partial undercast cloud cover.

The Air Force launched a humanitarian effort to immediately relieve the POWs suffering by dropping food supplies to the camps, which were spread all over the Far East.

It was a massive effort and the 73rd BW alone dropped 2,000 tons from 472 effective sorties to POW camps on the Japanese home islands,[11] Korea and China.

The plane lost an engine over the Rockies so they landed at Wright-Patterson AAF, Dayton, Ohio, and the photos were taken on by train to Washington, D.C. With victory in the Pacific achieved, the return of aircraft and crews not required for the occupation began under the Sunset Project.