333 North Michigan is a skyscraper in the art deco style located in the Loop community area of Chicago, Illinois in the United States.

Architecturally, it is noted for its dramatic upper-level setbacks that were inspired by the 1923 skyscraper zoning laws.

Designed by John Wellborn Root Jr., the building's long and narrow footprint and towering structure are a tribute to Root's father John Wellborn Root's earlier Chicago Monadnock Building; Louis Sullivan's tall-building canon; and Eliel Saarinen's second-prize entry in the Tribune Tower design contest.

The building's interior represents Prohibition era modernism, especially its Art Deco Tavern club.

[6] The building is embellished by a polished marble base, ornamental bands, and reliefs depicting frontiersmen and Native Americans at Fort Dearborn, which partially occupied the site.