The squadron flew combat missions in Southeast Asia from 13 March to 12 June 1965, 28 November 1965 – 7 October 1970, and c. 14 January–3 July 1973.

[1] In February 2015, the squadron was deployed to Spangdahlem Air Base, Germany, in support of Operation Atlantic Resolve.

[5] The A-10s were the first of several theater security package deployments to Europe, U.S. Air Force officials said, adding that rotations generally will last six months, depending on mission and United States European Command requirements.

[6] In mid-October 2023, the A-10 aircraft of the 354th Fighter Squadron were deployed to the US Central Command to enhance air operations throughout the Middle East in response to the 2023 Israel–Hamas war.

[7] This article incorporates public domain material from the Air Force Historical Research Agency