In World War I the regiment served overseas as a part of the 92nd Division, National Army and earned credit for battle participation as follows: The 366th Infantry was demobilized 25 March 1919 at Fort Oglethorpe, Georgia, and reconstituted 16 December 1940 in the Regular Army.

It was activated 15 October 1942 at Fort Devens, Massachusetts and assigned to the Eastern Defense Command on 30 April 1942.

Queen wrote a significant request for withdrawal from active command and included his guarded reservations in regard to his deeply held tenets.

[citation needed] After continuing poor combat performance, including many instances of unauthorized withdrawals upon meeting the enemy, low morale, and malingering, the 92nd Infantry Division was believed by both German and American commands to be fit for only defensive roles.

The 92nd Division commanders proposed that the "366th be removed from the front lines and disposed of as higher headquarters might direct," which was accepted.