The 368th Infantry Regiment was activated on 25 October 1917 at Camp Meade, Maryland as part of the 92nd Division.
The regiment returned to the United States after the Armistice and was demobilized at Camp Meade in February and March 1919.
The division was sent overseas in 1944 and participated in the New Guinea, Northern Solomons and Southern Philippines campaigns.
On 15 May 1951 the battalion was detached from the 82nd Airborne Division and relocated to Fort Sill, Oklahoma to support the United States Army Artillery Center.
About this time, the unit was desegregated, in line with a change in policy which abolished racial segregation in the U.S. Army.