The station is located on the campus of the University of Pennsylvania at the intersection of 37th and Spruce streets.

Trolleys serving this station go eastbound to Center City Philadelphia and westbound to the neighborhoods of Eastwick and Angora, as well as the Delaware County suburbs of Yeadon and Darby.

The station was opened in November 1955 by the Philadelphia Transportation Company (PTC) as part of a larger project to move portions of the elevated Market Street Line and surface trolleys underground.

[1] The original project to bury the elevated tracks between 23rd to 46th streets was announced by the PTC's predecessor, the Philadelphia Rapid Transit Company (PRT), in the 1920s, but was delayed due to the Great Depression and World War II.

In October 2006, Penn's class of 1956 donated a new covered headhouse for the eastbound platform entrance.