CUMYL-4CN-BINACA (also known as CUMYL-CYBINACA or SGT-78) is an indazole-3-carboxamide based synthetic cannabinoid that has been sold online as a designer drug.

[9] In mice, CUMYL-4CN-BINACA produces hypothermic and pro-convulsant effects via the CB1 receptor,[9] and anecdotal reports suggest it has an active dose of around 0.1 mg in humans.

[10] CUMYL-4CN-BINACA is metabolized to produce cyanide, raising concerns about liver toxicity.

[8] There is one reported case of hyperthermia, rhabdomyolysis, and kidney failure associated with its use.

[11] This cannabinoid related article is a stub.