The 455th Chemical Brigade is an NBC defense formation of the United States Army Reserve, active from 2000 to 2007 at Fort Dix.

The brigade traced its lineage back to the 100th Chemical Battalion (Motorized), constituted in the Army of the United States on 7 June 1944 during World War II, and activated on 5 August of that year at La Fagianeria, Italy.

[8] After deploying to Iraq, it initially supported Defense Threat Reduction Agency operations to eliminate Iraqi weapons of mass destruction while subordinated to the Combined Forces Land Component Command.

[2] Subsequently, following the end of major combat operations, it was transferred to the Iraq Survey Group (ISG), which was tasked with finding the Iraqi weapons of mass destruction.

[9] The 455th was chosen by Chemical Officers, BG Jim Blankenhorn and CPT Charles Hardenstine, to be reactivated in Sloan, Nevada under the 76th Operational Response Command.