ASD is responsible for the design, development and acquisition of aeronautical systems including transports, tankers and utility aircraft, rescue helicopters, long- and short-range air-to-surface missiles, aircraft engines and electronic warfare systems.

The majority of AFMC's large transport aircraft were assigned to the 4950th Test Wing and were loaned to other agencies as required.

Section updated by Major Tony Sylvain, Maj, USAF (Ret), 4950th OMS, 11 Jun 84 to 21 Jan 92.

These aircraft had multiple subtle differences evolved during design, most notable was the main crew door, which was hinged on the top and opened outward from the bottom.

Aircraft specifics: Section updated by Sgt Rob Schultz (FMS Engine Shop/4953rd AMU, 1986–1992), 26 April 2011