It saw service in France during World War I, earning battle honors for the Meuse-Argonne and Alsace 1918 campaigns.

The 54th Infantry Regiment was inactivated on 24 October 1922 at Fort Wayne, Michigan.

It has been the starting place for the training of tens of thousands of United States Army Infantrymen over the past three decades.

The unit was reactivated to enable the success of the army's new 22-week OSUT training regime.

[1] This article incorporates public domain material from the United States Army Institute of Heraldry