[2] Most recently, the brigade has served as the Task Force Medical-Afghanistan headquarters and was pivotal to the US Government response to the COVID-19 pandemic.

During its service in WWII, the 62nd Medical Brigade participated in four campaigns: Normandy, Northern France, Rhineland, and Central Europe and then was inactivated on 13 November 1945.

The multi-component task force had representation from the National Guard, Reserves, and active component that provided command and control, hospitalizations, ground and air evacuation, preventive medicine, combat stress, medical logistics, and area medical support.

The task force provided Level III hospitalization, vet services, PM, mental health, combat stress, logistics, ground and air evacuation operations throughout CENTCOM area of responsibility.

Level III hospitalization was performed by Expeditionary Medical Facility (EMF) Portsmouth and Dallas (USN), vet services by 993rd and 64th Vet Detachment (USA), preventive medicine services by FDPMU-E (USN), mental health services by COSTAF (USAF), combat stress services by (USN), logistical support by Forward Team, 6th MMLC and the 551st Medical Logistics Company (USA), ground evacuation by the 514th Medical Company (GA) (USA), and air evacuation by the 236th Medical Company (AA) (USA).

The 62nd Medical Brigade Headquarters served as the command and control (C2) element as Task Force Medical-Afghanistan (TF MED-A)[4] from June through December 2013.

Primary responsibilities included the coordination of all medical assets for the Army, Navy, and Air Force at echelons above brigade combat team (EABCT) throughout Afghanistan.