Be prepared to assume Medical Task Force mission command and conduct split based operations as required.

The 14th Combat Support Hospital has participated in World War II in the Aleutian Islands, Rhineland, and Central Europe.

In January 2006, the 14th Combat Support Hospital deployed to Afghanistan in support of Combined Joint Task Force-76 and the International Security Assistance Force- Afghanistan (ISAF) during Operation Enduring Freedom VII.

In June 2014, the 14th CSH assumed a Severe Weather Response Force mission.

[2] In October 2017, the 14th CSH provided aid to Puerto Rico as relief effort after Hurricane Maria devastated the island.