Until 1932 the brigade didn't maintain a headquarters and was assigned to the Seventh Corps Area.

[1] The brigade was organised as follows after formation:[1] From 1928 to 1931 the brigade was redesignated as 'Regular Army Inactive' and maintained training through an affiliation with the 14th Cavalry Regiment, and conducted training at Fort Des Moines, Iowa.

On 22 October 1945 the group was inactivated at Camp Myles Standish, Massachusetts, and disbanded 2 July 1952.

[4] On 21 February 1975 the 6th Cavalry Brigade was reconstituted at Fort Hood, Texas in the Regular Army and subsequently assigned to the III Corps.

In the autumn of 1990, two subordinate units of the brigade (including the 2nd Battalion, 158th Aviation Regiment), were deployed to Saudi Arabia.