[1] The cartridge was introduced by Federal Premium Ammunition loaded with long, heavy bullets for superior ballistic coefficients.
[2] Although the rimless cartridge uses the same .472 in (12.0 mm) diameter as early 20th-century military cartridges widely used as a basis for civilian hunting ammunition, the pressure increase to 80,000 psi (550,000 kPa) from the long-established SAAMI limit of 65,000 psi (450,000 kPa) may make the cartridge unsuitable for 20th-century firearm actions like the Gewehr 98, M1903 Springfield, and contemporary civilian models.
[1] The cartridge uses a propellant presently unavailable for handloading and available smokeless powders may not be designed for that pressure.
Resizing the fired steel case may be difficult with traditional handloading equipment.
The high design pressure produces relatively intense muzzle blast from short barrels encouraging use of suppressors which are heavily regulated in some jurisdictions.