It was last assigned to the 456th Strategic Aerospace Wing, stationed at Beale Air Force Base, California.

After training in the United States, it deployed to the European Theater of Operations and participated in the strategic bombing campaign against Germany.

[1] Following the attack on Pearl Harbor the squadron began flying antisubmarine patrols off the Atlantic coast.

[1] By the fall of 1942, the U-boat threat along the Atlantic coast had substantially diminished, but German wolfpacks were attacking merchant shipping in the waters near Trinidad.

In April 1943, the squadron began operating from Edinburgh Field, where it joined elements of the 25th Bombardment Group, a Sixth Air Force unit, that was also engaged in antisubmarine patrols.

Its initial missions were flown to prepare for Operation Overlord, the invasion of Normandy, as the squadron concentrated on targets in France.

[10][11] Once transition to the B-17 was completed on 24 August, the squadron concentrated on strategic bombing, attacking oil refineries, airfields, marshalling yards, and factories manufacturing aircraft and armored vehicles.

In the last month of the war in Europe, it carried out interdiction missions to support advancing ground forces.

[11] Following V-E Day, the squadron carried food to flooded areas of the Netherlands and transported prisoners of war to Allied repatriation centers.

[10] The air echelon began flying its planes back to the United States on 6 July 1945.

[13] On 19 November 1964, Defense Secretary Robert S. McNamara announced the phase-out of remaining first-generation Titan I missiles by the end of June 1965.

[13][14] This article incorporates public domain material from the Air Force Historical Research Agency