The 88th Regiment, Pennsylvania Volunteer Infantry was an infantry regiment that served in the Union Army during the American Civil War.
The 88th Pennsylvania Infantry was organized at Philadelphia, Pennsylvania and mustered in for a three-year enlistment in September 1861 under the command of Colonel George P. McLean.
The regiment was attached to 1st Brigade, Ord's 2nd Division, Department of the Rappahannock, to June 1862.
2nd Brigade, 2nd Division, III Corps, Army of Virginia, to September 1862.
2nd Brigade, 2nd Division, I Corps, Army of the Potomac, to March 1863.
The 88th Pennsylvania Infantry mustered out of service June 30, 1865.
(Companies A, C, D, E, and I garrisoned forts on the Maryland side of the Potomac River February 18 to April 17.)
Guarded the Orange & Alexandria Railroad between Bull Run and Fairfax Court House until May 7.
Expedition to Front Royal to intercept Jackson May 25-June 18.
Operations at Pollock's Mill Creek April 29-May 2.
Battle of the Wilderness May 5–7; Laurel Hill May 8; Spotsylvania May 8–12; Spottsylvania Court House May 12–21.
Mine Explosion, Petersburg, July 30, 1864 (reserve).
Warren's Expedition to Weldon Railroad December 7–12.
Dabney's Mills, Hatcher's Run, February 5–7, 1865.