In 1992, the 96th Anti-aircraft Missile Brigade of the Soviet Army came under the jurisdiction of Ukraine, becoming a part of the.Ukrainian Air Force.

[3] The brigade's equipment and personnel normally take part in the military parade on the Independence Day of Ukraine.

[4] On the afternoon of 2 February 2016, while patrolling the territory near Spirne, the personnel of the Brigade noticed movement several hundred meters away, they searched but found no one, while returning they blew up a landmine killing two soldiers of the brigade (Samus Gennadiy Vasyliovych[5] and Leonid Eduardovych Kozoroz[6]) and wounding four other soldiers of the brigade.

The brigade engaged Russian troops since 24 February 2022, the day of the start of the Russian invasion of Ukraine with a soldier of the brigade (Viktor Vyacheslavovych Kuzmin) being killed near Svatove on the day one of the invasion.

[9] On 27 June 2023, the brigade's commander Serhii Volodymyrovych Yaremenko was awarded the "Hero of Ukraine", the highest military award for Ukrainian personnel,[10][11] for the brigade's shooting down of 13 Kh-47M2 Kinzhal hypersonic missiles, according to the Ukrainian Air Force.