[10] The following season, after McNabb and Detmer went down with injuries, the 8–3 Eagles called on Feeley to preserve the team's Super Bowl aspirations.

[20] Their star running back Ricky Williams retired prior to the season after a failed drug test, and head coach Dave Wannstedt resigned from the team following a 1–8 start.

With the Dolphins trailing by 11 with just 3:59 to play, Feeley guided the team to two late scores, including a game-winning touchdown to Derrius Thompson to upset the defending Super Bowl champions.

[31] When McNabb was injured for the season on November 18, 2006, there was speculation that the more youthful Feeley might be named as the new starting quarterback, but head coach Andy Reid went with Jeff Garcia, who led the Eagles to a late-season turnaround and division title.

[33] Despite Garcia's success from the previous season, the Eagles viewed Feeley as a better long-term backup because of his age, familiarity of the system, and fit in the locker room.

[34] Starting in place of an injured Donovan McNabb on November 25, Feeley threw for 345 yards and three touchdowns with three interceptions in a 31–28 game loss to the then-undefeated New England Patriots.

[35] The 10–0 Patriots had beaten opponents by an average of 25 points, and the Eagles entered the game as the largest underdogs in NFL history at the time.

During the 2011 regular season, Feeley replaced an injured Bradford for three games and he led the Rams to a stunning upset of the New Orleans Saints on October 30.

[45] In 2010, Feeley married U.S. women's international soccer player Heather Mitts in Cabo San Lucas, Mexico.

[citation needed] On January 30, 2014, the couple gave birth to a baby boy, Connor William Feeley,[48] and a daughter, Blake Harper, followed in spring 2016.