It runs south-west into the foothills of the North Downs from West Wickham in the London Borough of Bromley through Addington, Forestdale, Selsdon, Sanderstead, Purley, the Woodcote part of that town, Banstead in Surrey and Epsom Downs through which it descends to a similar altitude as at its beginning to end at Epsom.

The A2022 starts in West Wickham in the London Borough of Bromley at a roundabout with the A232 and a minor road, of which it acts as a continuation, as Addington Road 1 mile (1.6 km) before entering the London Borough of Croydon.

[1] The Purley to Nork westerly less straight, curved hill-cross route starts at a set of traffic lights with the A23, part of the Purley Cross system as Foxley Lane and it climbs through the Woodcote locality, before it comes to a mini roundabout with Woodcote Road and Smitham Bottom Lane (both A237).

The A2022 becomes Fir Tree Road and heads west, passes within 50m of Banstead railway station in the Nork locality westwards; then it stops at the crossroads by the Drift Bridge, 500m short of Epsom Downs railway station, where it co-runs with the A240 and faces the B291 (also Fir Tree Road).

The road at Epsom is home to the Upper High Street which includes a large Odeon cinema and the Laine Theatre Arts.