South of Clapham Common station, the London Underground Northern line runs beneath the A24, following its route southbound.

Along this stretch of road, Cycle Superhighway 7 (CS7), which begins in the City of London, leaves the A3/Clapham High Street and follows the route of the A24.

The A24 and CS7 enter the London Borough of Merton as they cross via a railway bridge over the Sutton Loop Line, between Haydons Road and Tooting stations.

The road enters the North Cheam area of the London Borough of Sutton just before it reaches the Woodstock junction with the B279.

It passes the Sutton Common area to the east and runs down the steep Stonecot Hill before it changes name to London Road.

It passes St Anthony's Hospital on the way into North Cheam before reaching the Queen Victoria crossroads with the A2043.

At this point, the speed limit increases to 40 mph and the road subsequently runs alongside Nonsuch Park.

It passes a crossroads with the Ewell terminus of the A232 and the B2200 before running past the North East Surrey College of Technology, then approaches a roundabout with Reigate Road and the A240.

It passes Epsom General Hospital before beginning its long rural stretch to the south coast, first passing The Wells and Epsom Common before leaving the borough on a bridge over the Rye brook, a tributary of the River Mole.

The A24 runs next to Box Hill, passes two car parks and crosses the Burford Bridge over the River Mole.

The road continues past a roundabout with the A264 where it turns right to form part of the Horsham by-pass.

The dual carriageway continues past Southwater, the crossroads junction with the A272, Ashington, Washington and Findon before terminating in the seaside resort of Worthing at the A259 in the town centre.