This is a busy entry point used by people travelling by road between South Africa, Malawi, Zimbabwe and Mozambique.

[1][2][3] It starts at intersection with Samora Machel Avenue; however Enterprise Road itself begins from the T-junction with Robert Mugabe Avenue, opposite the market in Eastlea, east of Simon Muzenda Street (Fourth Street) Road Port; a bus terminus for inter-regional buses.

[6] The A2 Highway known as Mutoko Road, Mutoko being popular as a mango and tomato supplier to Mbare Musika the largest green market in Harare and all Zimbabwe.

[7] As a regional corridor the A2 is known as the R4 Highway relays traffic from South Africa to Malawi.

From Harare to Lilongwe using the A2/R4 Highway and Mozambique's Route 222 the distance is about 741 km (460.4 miles).