It is the main road that gives access to the Jodrell Bank Observatory and the Quinta Arboretum, planted by Sir Bernard Lovell in 1948.

[2][3][4] In medieval times part of the existing A535 route provided access to Chorley Old Hall and moat near Alderley Edge, a Grade I listed building and scheduled monument.

They built a grand mansion at Twemlow Hall in the area which can be viewed along the A535 road from Holmes Chapel to Goostrey on a hill top.

[12] The first major constructional work was completed in the summer of 1957, and eventually five telescopes were installed at the centre under the guidance of Sir Bernard Lovell.

After the gentle climb out of Twemlow, the Lovell Telescope of Jodrell Bank is in view, with access to the site being from a sharp left turn into Bomish Lane.

[15] Further north is Farm Wood Quarry on its left, an area which the road passes which has had several notable geological examinations conducted into it.