The A62 road in Northern England runs between the cities of Leeds in West Yorkshire and Manchester in Greater Manchester covering a distance of 38.5 miles (62.0 km).

It runs through West Yorkshire, passing through Birstall, Heckmondwike, Liversedge, Huddersfield, Linthwaite, Slaithwaite, and Marsden.

It crosses the Pennines at Standedge, and continues through Saddleworth and into Oldham.

It is paralleled at some distance by part of the M62 Trans-Pennine motorway.

Before the M62 was built, the A62 was the main trans-Pennine road between Oldham and Huddersfield.