864727413ENSG00000276582ENSG00000073734ENSMUSG00000027048O95342Q9QY30NM_003742NM_021022NM_001363492NP_003733NP_066302NP_001350421ATP-binding cassette, sub-family B member 11 (ABCB11), also known as the bile salt export pump (BSEP), is a protein which in humans is encoded by the ABCB11 gene.
[5] The product of the ABCB11 gene is an ABC transporter named BSEP (bile salt export pump), or sPgp (sister of P-glycoprotein).
ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This particular protein is responsible for the transport of taurocholate and other cholate conjugates from hepatocytes (liver cells) to the bile.
[16] This article incorporates text from the United States National Library of Medicine, which is in the public domain.