The club was formed under the name Duke of York in 1971, as founder members of the North West Women's League.

and finished 1997–98 as champions, winning promotion to the Northern Combination Women's Football League.

One month later, on 26 May 2020, AFC Fylde reversed its decision, thus saving the club.

In August 2018, they briefly moved in with their male counterpart team at Mill Farm, training at The Fylde Sports and Education Centre.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.