and Matthew Rushton, Hollywood film producer of Mrs. Doubtfire, founded Search Alliance to speed the discovery and development of effective treatments against HIV and its complications.

[7] Working with physicians who were experimenting with potential treatments in their private practices, the organization pooled data and identified promising experimental regimens.

[19] ARAA conducted clinical trials aimed at treating the medical disorders that accompany HIV, including HIV-associated lipodystrophy,[20] diarrhea and neuropathy.

ARAA conducted clinical trials for major pharmaceutical sponsors including Pfizer, Merck, Theratechnologies, Schering-Plough, Tibotec, NeurogesX, National Institutes of Health, Serono, Bristol-Myers Squibb, Agouron, GlaxoSmithKline, Orasure Technologies, Gilead Sciences, and many others.

[25][26][27][28] Funders and partners to ARAA included The Ahmanson Foundation, Capital Group Companies, City of West Hollywood, Concord Music Group, David Michod, Douglas MacBride Kinney, Entertainment AIDS Alliance, The Joseph Drown Foundation, Kaiser Permanente, MacHeist,[29] The MacDonald Family Foundation, The Pepsi Refresh Project, The Silva Watson Moon Walk Fund, The University Wide AIDS Research Program [the University of California], the Division of AIDS [NIH], Until There is a Cure, and many others.