4CAY, 4NFT8161166471ENSG00000143401ENSMUSG00000015749Q9BTT0P97822NM_001136478NM_001136479NM_001280559NM_001280560NM_030920NM_001253757NM_001253758NM_023210NP_001129950NP_001129951NP_001267488NP_001267489NP_112182NP_001240686NP_001240687NP_075699Acidic leucine-rich nuclear phosphoprotein 32 family member E is a protein that in humans is encoded by the ANP32E gene.

[5][6] The ANP32E gene is located on chromosome 1q22.

[5] In mammalian cells, ANP32E has been shown to be an H2A.Z chaperone capable of promoting the removal of H2A.Z from chromatin.

[7] In brain tissue, ANP32E together with Cpd1 regulate protein phosphatase 2A activity at synapses during synaptogenesis[8] and has been observed to form a complex with ANP32A and SET that stabilizes short-lived mRNAs containing AU-rich elements, as well as having acetyltransferase inhibitory activity (in a complex with SET) and having a role in chromatin remodeling and transcriptional regulation.

[9] This article on a gene on human chromosome 1 is a stub.