[5] This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes.

The encoded protein may play a role in clathrin-mediated endocytosis.

Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 17 is a stub.