2EE4, 2EE539411855ENSG00000100852ENSMUSG00000035133Q13017P97393NM_001030055NM_001173NM_009706NP_001025226NP_001164NP_033836Rho GTPase-activating protein 5 is an enzyme that in humans is encoded by the ARHGAP5 gene.

[5][6] Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family that may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP.

Two transcript variants encoding different isoforms have been found for this gene.

[6] ARHGAP5 has been shown to interact with Rnd1,[7] Rnd2,[7] Rnd3[7] and RHOA.

This article on a gene on human chromosome 14 is a stub.