5EFX918116800ENSG00000116584ENSMUSG00000028059Q92974Q60875NM_001350112NM_001198911NM_001198912NM_001198913NM_008487NM_001377126NP_001337041NP_001185840NP_001185841NP_001185842NP_032513NP_001364055Rho guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the ARHGEF2 gene.

[5][6][7] Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein-coupled receptors.

The encoded protein may form complex with G proteins and stimulate rho-dependent signals.

[7] ARHGEF2 has been shown to interact with PAK1.

This article on a gene on human chromosome 1 is a stub.